City Temple engages in the ministry of prayer in a number of ways. In addition to various ad hoc groups for prayer, City Temple has regular times of prayer, including Monday and Wednesday lunchtime prayer fellowships, Friday nights and other regular gatherings.

City Temple also maintains a prayer chapel open to the public whenever the building is open. People use this chapel regularly for prayer throughout the week. City Temple also provides other occasional times for prayer, such as all-night prayer events and 24/7 prayer for specified periods.

City Temple offers ministry to people through prayer. In particular, City Temple provides a prayer process called the “Steps to Freedom in Christ”, whereby a person might receive directed ministry and coaching through prayer. City Temple encourages and trains people to minister to others through Christian prayer, seeking to meet people where they are in this vital ministry.